Long-‐life supplementation with atenolol…
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Figure 5.-‐
Protein oxidation, glycoxidation and lipoxidation indicators in SKM mitochondria from
control and atenolol treated mice. Values are means ± SEM from 6 different animals and are
expressed as percentage of those in the controls for each protein modification marker. Control
values: 4,415±272 (glutamic semialdehyde, GSA); 463±24 (AASA, aminoadipic semialdehyde,
AASA); 380±25 (carboxyethyl-‐lysine, CEL); 770±48 (carboxymethyl-‐lysine, CML); 632±65
(malondialdehyde-‐lysine, MDAL). Units: µmol/mol lysine. Asterisks represent significant
differences between the control and the atenolol group. ** P<0.01; *** P<0.001.
Figure 6.-‐
Ratio p-‐ERK/total ERK. Ratio of phosphorylated versus total ERK (nonphosphorylated)
(p-‐ERK/ERK); ERK represents the sum of the 44-‐kD and the 42-‐kD ERK proteins. Values presented
are means_standard error of the mean (SEM) from n=4 different animals per group over
immunoreactivity in control values. Asterisk represents significant differences compared to values
of untreated animals. (*) p<0.05.
