An. Real. Acad. Farm. vol 79 nº 4 2013 - page 115

Alexia Gómez & col.
630
2.
Barja, G.; Cadenas, S.; Rojas, C.; Pérez-­‐Campo, R.; López-­‐Torres, M., Low mitochondrial free
radical production per unit O
2
consumption can explain the simultaneous presence of high
longevity and high aerobic metabolic rate in birds. Free Rad Res
1994
; 21, 317–327
3.
Barja, G.; Mitochondrial oxygen consumption and reactive oxygen species production are
independently modulated: implications for aging studies.
Rejuv Res
200
7;
10
, 215–224
4.
Pamplona, R.; Portero Otín, M.; Riba, D.; Ruiz, C.; Prat, J.; Bellmunt, M.J.; Barja, G.
Mitochondrial membrane peroxidizability index is inversely related to maximum life span
in mammals.
J Lipid Res
1998
;
39
, 1989-­‐94
5.
Hulbert, A.J.; Pamplona, R.; Buffestein, R.; Buttemer, W.A. Life and death: metabolic rate,
membrane composition and life span of animals.
Physiological Reviews
2007
;
87
, 1175-­‐
1213
6.
Hagopian, K.; Chen, Y.; Simmons Domer, K.; Soo Hoo, R.; Bentley, T.; McDonald, R.B.;
Ramsey, J.J. Caloric restriction influences hydrogen peroxide generation in mitochondrial
sub-­‐populations from mouse liver.
J Bioenerg Biomembr
2011
;
43
, 227-­‐36
7.
Gredilla, R.; Barja, G. Caloric restriction, aging and oxidative stress.
Endocrinology
2005
;
146
, 3713–3717
8.
Sanz, A.; Caro, P.; Barja, G. Protein restriction without strong caloric restriction decreases
mitochondrial oxygen radical production and oxidative DNA damage in rat liver.
J Bioenerg
Biomembr
2004
;
36
, 545–552
9.
Sanz, A.; Caro, P.; Ayala, V.; Portero-­‐Otin, M.; Pamplona, R.; Barja, G. Methionine restriction
decreases mitochondrial oxygen radical generation and leak as well as oxidative damage
to mitochondrial DNA and proteins.
FASEB J
2006a
;
20
, 1064–1073
10.
Pamplona, R.; Barja, G. An evolutionary comparative scan for longevity-­‐related oxidative
stress resistance mechanisms in homeotherms.
Biogerontology
2011
;
12
, 409:35
11.
Shmookler Reis, R.J.; Xu, L.; Lee, H.; Chae, M.; Thaden, J.J.; Bharill, P.; Tazearslan, C.; Siegel,
C.; Alla, R.; Zimniak, P.; Ayyadevara, S. Modulation of lipid biosynthesis contributes to
stress resistance and longevity of C. elegans mutants.
Aging
2011
; 3, 125–147
12.
Hulbert, A.J. Metabolism and longevity: Is there a role for membrane fatty acids?
Integr
Comp Biol
2010
;
50
, 808-­‐17
13.
Naudi, A.; Jove, M.; Ayala, V.; Portero-­‐Otin, M.; Barja, G.; Pamplona, R. Regulation of
membrane unsaturation as antioxidant adaptive mechanism in long-­‐lived animal species.
Free Rad Antiox
2011
;
1
, 3-­‐12
14.
Pratt, D.A.; Tallman, K.A.; Porter, N.A. Free Radical Oxidation of Polyunsaturated Lipids:
New Mechanistic Insights and the Development of Peroxyl Radical Clocks.
Acc Chem Res
2011
; 44, 458-­‐67
15.
Holman, R.T. Autoxidation of fats and related substances. In: Holman RT, Lundberg WO,
Malkin T (eds) Progress in chemistry of fats and other lipids.
Pergamon Press, London
,
1954
; 51–98
16.
Pamplona, R.; Barja, G.; Portero-­‐Otín, M. Membrane fatty acid unsaturation, protection
against oxidative stress, and maximum life span: a homeoviscous-­‐longevity adaptation.
Ann New York Acad Sci
2002
;
959
, 475-­‐490
17.
Liang, H.; Masoro, Nelson, J.F.; Strong, R.; McMahan, C.A.; Richardson, A. Genetic mouse
models of extended lifespan.
Exp Gerontol
,
2003
;
38,
1353–1364
18.
Selman, C.; Withers, D.J. Mammalian models of extended healthy lifespan
. Philos Trans R
Soc Lond B Biol Sci
2011
;
366
, 99-­‐107
19.
Narasimhan, S.D.; Yen, K.; Tissenbaum, H.A. Converging pathways in lifespan regulation.
Curr Biol,
2009
;
19
, 657-­‐6
20. Selman, C.; Tullet, J.M.A.; Wieser, D.; Irvine, E.; Lingard, S.J.; Choudhury, A.I.; Claret, M.; Al-­‐
Qassab, H.; Carmignac, D.; Ramadani, F.; Woods, A.; Robinson, I.C.A.; Schuster, E.;
Batterham, R.L.; Kozma, S.C.; Thomas, G.; Carling, D.; Okkenhaugk, K.; Thornton, J.M.;
1...,105,106,107,108,109,110,111,112,113,114 116,117,118,119,120,121,122,123,124,125,...190
Powered by FlippingBook