An. R. Acad. Farm. vol 79 nº 1 2013 - page 170

J. R. Lacadena y F. Mayor Menéndez
170
pluripotent stem cells generated from patients with ALS can be differentiated into motor
neurons. Science 321, 1218-­‐1221 (2008).
39.
Park, I.H. et al. Disease-­‐specific induced pluripotent stem cells. Cell 134, 877-­‐886 (2008).
40.
Ebert, A.D.; Yu, J.; Rose Jr, F.F.; Mattis, V.B.; Lorson, C.L.; Thomson, J.A.; Svendsen, C.N.
Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-­‐
281 (2009).
41.
Marchetto, M.C.N.; Carromeu, C.; Acab, A.; Yu, D.; Yeo, G.W. ; Mu, Y.L. et al. A model for
neural development and treatment of Rett syndrome using human induced pluripotent
stem cells. Cell 143, 527-­‐539 (2010).
42.
Rashid, S.T.; Corbineau, S.; Hannan, N. ; Marciniak, S.J. ; Miranda, E. ; Alexander, G. et al.
Modeling inherited metabolic disorders of the liver using human induced pluripotent
stem cells. J. Clin. Invest. 120, 3127-­‐3136 (2010).
43.
Liu, G-­‐H.; Barkho, B.Z.; Ruiz, S.; Diep, D.; Qu, J.; Yang, S-­‐L.; panopoulos, A.D.; Suzuki, K.;
Kurian, L.; Walsh, C.; Thompson, J.; Boue, S.; Fung, H.L.; Sancho-­‐Martínez, I.; Zhang, K.;
Yates, J. III; Izpisua Belmonte, J.C. Recapitulation of premature ageing with iPSCs from
Hutchinson-­‐Gilford progeria syndrome. Nature doi:10.1038/nature09879 (2011)
44.
Koch, P.; Breuer, P.; Peitz, M.; Jungverdorben, J. ; Kesavan, J.; Poppe, D. et al. Excitation-­‐
induced ataxin-­‐3 aggregation in neurons from patients with Machado-­‐Joseph disease.
Nature 480, 543-­‐546 (2011).
45.
IsraeL, M.A.; Yuan, S.H.; Bardy, C.; Reyna, S.M.; Mu, Y.; Herrera, C. et al. (2012) Probing
sporadic and familial Alzheimer’s disease using induced pluripotent stem cells. Nature
482, 216-­‐220 (2012).
46.
The HD iPSC Consortium. Induced pluripotente stem cells from patients with Huntington’s
disease show CAG-­‐repeat-­‐expansion-­‐associated phenotypes. Cell Stem Cell 11, 264-­‐278
(2012).
47.
Liu, G-­‐H; Qu, J.; Suzuki, K.; Nivet, E.; Li, M.; Montserrat, N.; Yi, F. ; Ruiz, X.S. ; Zhang, W. ;
Wagner, U.; Kim, A.; Ren, B.; Li, Y.; Goebl, A.; Rupa, J.K.; Soligalla, D.; Dubova, I.; Thomson,
J.; Yates III, J.; rodriguez, G.; Sancho-­‐Martínez, E.I.; Izpisua Belmonte, J.C. Progressive
degeneration of human neural stem cells caused by pathogenic LRRK2. Nature
doi:10.1038/nature 11557 (2012).
48.
Brennand, K.J.; Simone, A.; Jou, J.; Gelboin-­‐Burkhart, C.; Tran, N.; Sanger, S. et al. Modelling
squizophrenia using human induced pluripotent stem cells. Nature 473, 221-­‐225 (2011).
49.
Kennedy, D. Editorial. Breakthrough of the year. Science 318:1833 (2007). Ford, M.
Science magazine’s top 10 breakthroughs of the year. Science (2008).
50.
Evans, M.J.; Kaufman, M.H. Establishment in culture of pluripotential cells from mouse
embryos. Nature 292, 154-­‐156 (1981).
51.
Thomson, J.A.; Itskovitz-­‐Eldor, J.; Shapiro, S.S.; Waknitz, M.A.; Swiergiel, J.J.; Marshall, V.S.;
Jones, J.M. Embryonic stem cells derived from human blastocystes. Science 282, 1145-­‐
1147 (1998).
52.
Cibelli, J.B.; Kiessling, A.A.; Cunniff, K.; Richards, C.; Lanza, R.P.; West, M.D. Somatic cell
nuclear transfer in humans: Pronuclear and early embryonic development. E-­‐biomed: The
Journal of Regenerative Medicine 2, 25-­‐31 (2001). Cibelli, J.B.; Lanza, R.P.; West, M.D.;
Ezze
bryo. Scient. Am. 286, 42-­‐49 (2002).
53.
NIH.
(diciembre 2012)
54.
Had
ion and transdetermination. Brookhaven Symp. Biol.
No. 18 (Genetic control of differentiation), 148-­‐161 (1965).
55.
.; Perimann, T. Mature cells can be reprogrammed to become
Nobel Prize in Physiology or Medicine – Advanced Information.
(2012)
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